Drug Interaction Alert: Potential Risk with Paxlovid and Apixaban
Important Information for Healthcare Professionals
Healthcare professionals are advised that coadministration of Paxlovid (nirmatrelvir/ritonavir) with apixaban may increase apixaban concentrations, potentially leading to an increased bleeding risk.
Assessment Guidelines
According to Liverpool COVID-19 Drug Interactions website, this interaction is considered a "potential clinically significant interaction that is likely to require additional monitoring."
Healthcare professionals should refer to the Apixaban Summary of Product for further guidance on potential interactions.
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